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Science/Tech
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Title: Ancient Greenland gene map has a surprise
Source: Reuters
URL Source: http://news.yahoo.com/s/nm/20100210/sc_nm/us_human_genes
Published: Feb 11, 2010
Author: Maggie Fox
Post Date: 2010-02-11 14:01:51 by F.A. Hayek Fan
Keywords: None
Views: 149
Comments: 4

WASHINGTON (Reuters) – Scientists have sequenced the DNA from four frozen hairs of a Greenlander who died 4,000 years ago in a study they say takes genetic technology into several new realms.

Surprisingly, the long-dead man appears to have originated in Siberia and is unrelated to modern Greenlanders, Morten Rasmussen of the University of Copenhagen and colleagues found.

"This provides evidence for a migration from Siberia into the New World some 5,500 years ago, independent of that giving rise to the modern Native Americans and Inuit," the researchers wrote in Thursday's issue of the journal Nature.

Not only can the findings help transform the study of archeology, but they can help answer questions about the origins of modern populations and disease, they said.

"Such studies have the potential to reconstruct not only our genetic and geographical origins, but also what our ancestors looked like," David Lambert and Leon Huynen of Griffith University in Queensland, Australia, wrote in a commentary.

The DNA gives strong hints about the man, nicknamed Inuk. "Brown eyes, brown skin, he had shovel-form front teeth," Eske Willerslev, who oversaw the study, told a telephone briefing. Such teeth are characteristic of East Asian and Native American populations.

He had the genes for early hair loss, too. "Because we found quite a lot of hair from this guy, we presume he actually died quite young," Willerslev said.

The man lived among the Saqqaq people, the earliest known culture in southern Greenland that lasted from around 2500 BC until about 800 BC.

Scientists have disagreed on who these people were -- whether they descended from the peoples who crossed the Bering Strait 30,000 to 40,000 years ago to settle the New World or whether they were more recent immigrants.

Willerslev's team pulled DNA from hairs found in a frozen Saqqaq site and sequenced it just as they would a modern person's full genome, looking for characteristic mutations.

"Recent advances in DNA sequencing technologies have initiated an era of personal genomics," the researchers wrote.

"The sequencing project described here is a direct test of the extent to which ancient genomics can contribute knowledge about now-extinct cultures," they added.

The DNA links Inuk to modern-day Arctic residents of Siberia. He had almost none of the mutations seen in Indians living in Central and South America.

"We have an increasingly powerful forensic tool with which to 'reconstruct' extinct humans and the demographics of populations," Lambert and Huynen wrote.

A year ago scientists sequenced the genome of a Neanderthal -- early humans who went extinct 30,000 years ago -- and other groups have sequenced DNA from dried-out mammoth hair.

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#1. To: F.A. Hayek Fan (#0)

As a tried and true celt, I heart this DNA sequencing. Not for the reasons of this article, but because it shows so many interesting links for most of Europe to either celts, germans or italics.

Neanderthals are just marshmallows on the hot chocolate.

As always I wonder how the basques fit in, outside of being the source of the Gaels.

MapQuest really needs to start their directions on #5. Pretty sure I know how to get out of my neighborhood.

SonOfLiberty  posted on  2010-02-11   23:10:25 ET  Reply   Trace   Private Reply  


#2. To: SonOfLiberty (#1)

As always I wonder how the basques fit in, outside of being the source of the Gaels.

Here's what Wikipedia says about their Genetics:

Although they are genetically distinctive in some ways, the Basques are still very typically West European in terms of their Mt-DNA and Y-DNA sequences, and in terms of some other genetic loci. These same sequences are widespread throughout the western half of Europe, especially along the western fringe of the continent. The Sami people of northern Scandinavia show an especially high abundance of a Mt-DNA type found at 11% among Basques. Somewhat higher among neighbouring Cantabrians, the isolated Pasiegos have a Mt-DNA V haplogroup of wider microsatellite variation than Sami.[31][32][33] Autosomal genetic studies confirm that Basques have a very close relationship with other Europeans, especially with Spaniards - who have a common genetic identity of over 70% with Basques.[34] In fact, according to a Europe-wide study, the main components in the European genomes appear to derive from ancestors whose features were similar to those of modern Basques and Near Easterners, with average values greater than 35% for both these parental populations, regardless of whether or not molecular information is taken into account. The lowest degree of both Basque and Near Eastern admixture is found in Finland, whereas the highest values are, respectively, 70% ("Basque") in Spain and more than 60% ("Near Eastern") in the Balkans.[35][36] Before the development of modern genetics based on DNA sequencing, Basques were noted as having the highest global apportion of the Rh- blood type (35% phenotypically, 60% genetically). Additionally, the Basque population has virtually no B blood type, nor the related AB type. These differences are thought to reflect their long history of isolation, as well as times during which the Basque population contracted, allowing genetic drift to dramatically influence genetic makeup. The history of isolation reflected in gene frequencies has presumably also been key to the retention of the distinctive Basque language. In fact, in accordance with other genetic studies, a recent genetic piece of research from 2007 claims: "The Spanish and Basque groups are the furthest away from other continental groups (with more diversity within the same genetic groups) which is consistent with the suggestions that the Iberian peninsula holds the most ancient West European genetic ancestry." Since the Basques speak a non-Indo-European language and have the highest proportion of the Rh negative blood type of all the peoples of the world, they were widely considered to be a genetically isolated population, preserving the genes of European Palaeolithic hunter-gatherers, until recent genetic studies found that modern Basques have a common ancestry with other Western Europeans.[37] The similarity includes the predominance in their male populations of Y-chromosome Haplogroup R1b, now considered to have been spread through Europe by new arrivals in the Neolithic period or later.[38] mtDNA Haplogroup V was initially thought to have spread through Europe after the last Ice Age from a refuge in what is now the Basque Country.[39] However studies have found no V in ancient remains from three prehistoric sites in the Basque Country dating to 4000–5000 years ago.[40] In addition, haplogroup K (mtDNA), found at frequencies of 16%-23% in the prehistoric sites, is nearly absent from modern Basques, while haplogroup J (mtDNA) (thought to have arrived in Europe with Neolithic farmers), found in two prehistoric sites at a frequency of 16% and the early medieval necropolis at Aldaieta at 14.7%, has suffered a major reduction to 2.4% in modern Basques.[40] http://en.wikipedia.org/wiki/Basque_people#Genetics

"The Central Intelligence Agency owns everyone of any significance in the major media." ~ William Colby, Director, CIA 1973–1976

The purpose of the legal system is to protect the elites from the wrath of those they plunder.- Elliott Jackalope

"When plunder becomes a way of life for a group of men living together in society, they create for themselves in the course of time a legal system that authorizes it and a moral code that justifies it." - Frederic Bastiat

F.A. Hayek Fan  posted on  2010-02-11   23:21:53 ET  Reply   Trace   Private Reply  


#3. To: F.A. Hayek Fan (#2)

This suggests, to me, a longer link to proto-indo-european language than before. There is firm speculation that there are strong remnants of a paleolitithic language in the basques.

That said, the Irish seem to trace from the basques, and from the Irish the Scots and Manx.

Fun world we live in n'est-ce pas?

MapQuest really needs to start their directions on #5. Pretty sure I know how to get out of my neighborhood.

SonOfLiberty  posted on  2010-02-11   23:31:17 ET  Reply   Trace   Private Reply  


#4. To: SonOfLiberty (#3)

Fun world we live in n'est-ce pas?

certes oui!

"The Central Intelligence Agency owns everyone of any significance in the major media." ~ William Colby, Director, CIA 1973–1976

The purpose of the legal system is to protect the elites from the wrath of those they plunder.- Elliott Jackalope

"When plunder becomes a way of life for a group of men living together in society, they create for themselves in the course of time a legal system that authorizes it and a moral code that justifies it." - Frederic Bastiat

F.A. Hayek Fan  posted on  2010-02-11   23:34:49 ET  Reply   Trace   Private Reply  


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