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Health
See other Health Articles

Title: Exercise cuts risk of developing bowel cancer polyps
Source: [None]
URL Source: http://www.bbc.co.uk/news/health-12610236
Published: Mar 2, 2011
Author: Dominic Hughes
Post Date: 2011-03-02 00:39:39 by Tatarewicz
Keywords: None
Views: 52
Comments: 2

Colon Polyps Regular exercise reduces the risk of developing polyps which can lead to bowel cancer

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People who lead an active lifestyle are up to three times less likely to develop polyps which can develop into bowel cancer, according to a study.

The report pulls together 20 previous studies looking at the link between exercise and the development of large polyps.

Bowel cancer is the third most common cancer in the UK.

More than 38,000 people are diagnosed with the disease each year.

The work was done by scientists from the Washington University School of Medicine in St Louis in the US.

Publishing their findings in the British Journal of Cancer, they say they have produced the most accurate figures yet that show low exercise levels are linked to bowel polyps.

They found that people who take regular exercise were 16% less likely to develop bowel polyps and 30% less likely to develop large or advanced polyps. Continue reading the main story “Start Quote

The reality is that exercise is acting through more than one mechanism. The upside is there are so many benefits all over the body, it is hard to pinpoint”

End Quote Professor Kathleen Wolin Washington University School of Medicine

Polyps - also known as adenomas - are growths in the bowel and while they are not cancerous in themselves they can develop into cancer over a long period of time.

Cancer Research UK says most bowel cancers develop from a polyp and about 1 in 4 of us have one or more by the age of 50, while about half of us have them by the time we are 70.

But only a small fraction of polyps develop into cancer and it takes years for that to happen. Exercise link

Professor Kathleen Wolin, one of the lead authors of the research, says the evidence now shows a clear link between exercise and a reduced risk of bowel cancer but it is not yet clear exactly why that link exists.

"There are a number of likely pathways but we don't know exactly. So for example exercise reduces inflammation in the bowel, which has been linked to bowel cancer.

"But exercise also reduces insulin levels and improves the body's response to hyperinsulinaemia (excess levels of insulin circulating in the blood), which again increases polyp risk.

"It also enhances the immune system and because people who exercise often do so outside, they get vitamin D, which is also important for bowel cancer.

"The reality is that exercise is acting through more than one mechanism. The upside is there are so many benefits all over the body, it is hard to pinpoint." Keeping active

Sara Hiom, director of health information at Cancer Research UK, says the evidence shows that keeping active could help prevent thousands of cases of cancer every year.

"We'd recommend doing at least half an hour's moderate exercise a day - such as brisk walking or anything that leaves you slightly out of breath. Getting enough physical activity will also help you keep a healthy weight, which is one of the most important ways of reducing the risk of cancer."

Mark Flannagan, Chief Executive of Beating Bowel Cancer, backed the study and said it was clear that lifestyle was an important factor in protecting yourself from cancer.

"Although the majority of polyps are not cancerous, it is thought that almost all bowel cancers develop from polyps. Therefore we recommend taking 30 minutes of physical activity each day, along with a healthy diet and lifestyle, to reduce your risk of developing bowel cancer."

Deborah Alsina, Chief Executive of Bowel Cancer UK, said the report was good news.

"Evidence also shows that the combination of taking more exercise and having a healthy diet may protect against bowel cancer, as well as weight gain and obesity, so we encourage people to do both.

"It is also important that people take part in the screening programme, if eligible, as screening is an effective means of detecting polyps at an early stage. These polyps can easily be removed, reducing the risk of bowel cancer developing."

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#1. To: Tatarewicz (#0)

They needed yet another study to know this? Who funded this study, taxpayers?

God is always good!

RickyJ  posted on  2011-03-02   0:42:33 ET  Reply   Trace   Private Reply  


#2. To: RickyJ (#1)

Just confirms earlier research, but you never know they may stumble upon what causes the polyps.

What are colon polyps?

A colon polyp is an outgrowth of tissue from the wall of the large bowel or colon. Polyps can vary in size. A polyp can look like a pea or a wart, sometimes a small mushroom on a stalk, or even resemble an area of raised carpet with many finger-like projections. There are many types of colon polyps, some of which carry no potential for developing into cancer and some that do.

Colon polyps may be single or multiple, very small in size or they may grow to 2 centimetres in diameter or larger. They are most common in Western countries. Adenomas and hyperplastic polyps

The 2 most common types of polyps are adenomas and hyperplastic polyps.

Colonic adenomas are more common as people get older. Doctors believe they may represent an increased risk for colorectal cancer, although they believe only a small number of adenomas develop into cancer and those that do take many years to do so. Hyperplastic polyps, although they do not involve a risk for colorectal cancer in themselves, can sometimes contain adenomas, especially if the hyperplastic polyps are large. What causes colon polyps?

The cause of colon polyps is unclear. Some evidence suggests that they may be related to unhealthy lifestyle factors. Smoking, being overweight, having a sedentary lifestyle, eating a diet that is high in fat and low in fibre, and drinking excess alcohol can increase your risk of colon polyps and colon cancer.

Genetic factors may also play a part, especially in people with a family history of colon polyps or colorectal cancer.

In a condition called familial polyposis, a hundred or more small polyps develop on the colon, so that it looks like a carpet of small raised lumps. Several members of a family may suffer from this condition, and there is a high risk that one or more of the polyps may turn malignant. For this reason, people who have a relative who has had polyps should have regular examinations and sometimes may need to have their colon removed to prevent cancer from developing. Usually people with familial polyposis who aren't treated go on to develop cancer by the age of 40.

Doctors estimate that adenomas of the colon occur in about 20 per cent of middle-aged and older adults, but it may be the case that only people with certain genetic profiles, or those who have large polyps, go on to develop colorectal cancer. What are the symptoms of colon polyps?

In most cases, polyps do not cause any symptoms and may only be discovered during a routine screening by your doctor. They may, however, bleed and you may see blood on your stool or from your rectum, or they will result in excessive mucus in your bowel motions. Sometimes (although this is rare), a large polyp may obstruct or block your bowel, which leads to constipation or diarrhoea, abdominal pain or vomiting. How are colon polyps diagnosed?

Because there are often no readily apparent symptoms, the diagnosis of colon polyps is usually made only after certain investigations are carried out, including:

* sigmoidoscopy or colonoscopy, which are both forms of endoscopy, in which a flexible lighted instrument (an endoscope) is inserted into the rectum to view part or all of the colon; and * X-ray barium studies of the large bowel, also called a barium enema. In this test a small tube is placed in the rectum, and barium and air are gently introduced. The barium will highlight the bowel so that any abnormalities will show up on X-ray.

Because polyps and early bowel cancer commonly have no symptoms, screening for bowel cancer is recommended. For the majority of people, a test known as a faecal occult blood test (FOBT) should be done once every 1-2 years after you turn 50. If the FOBT detects traces of blood in the bowel movements (faeces) your doctor will recommend another test – usually a colonoscopy. For people with a family history of bowel cancer or those with inflammatory bowel disease, screening may need to be more intensive, so consult your doctor. What can be done to prevent colon polyps?

* A diet that's high in fibre and calcium, and low in dietary fat may help protect against the development of colon polyps. Stopping smoking, keeping physically active and cutting down on alcohol may also help. * When an adenoma has been identified and removed, your doctor may recommend periodic screening by colonoscopy. Because this type of polyp can recur and does carry some risk of developing into colorectal cancer, regular checks are important. * There is some evidence that aspirin and similar drugs, known as non-steroidal anti-inflammatory drugs (NSAIDs), may protect against colonic adenomas, however, the evidence is not conclusive at present. Do not start taking aspirin without first asking the advice of your doctor.

How are colon polyps treated?

Rectal or colon polyps are generally removed because it has been shown that doing this significantly reduces a person's risk of getting colon cancer. Usually, they are removed during a colonoscopy. In the procedure, doctors manoeuvre a long wire loop through the colonoscope and around the base of the polyp. The loop is pulled tight, and then an electrical current is passed through the wire. This cauterizes the base of the polyp so that it can be removed without bleeding. This causes only minimal discomfort and the person can usually go home on the same day as the procedure. In rare cases where the polyp is very large, traditional surgery may be needed to remove it.

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I suspect the cause is dietary and possibly excess gas in the gut which when blocked by the bolus causes bulges to occur. The dietary part would be highlighted by a missing or inadequate/particular amino acid as the gut is being (re)built, thereby causing a weak spot. We were told in Biology 130 to never eat corn alone because it is missing one essential amino acid so always eat corn with some other protein-containing food so that whatever protein needs to be assembled in your body will have the aa's required for optimum structural strength/performance.

Tatarewicz  posted on  2011-03-02   2:57:42 ET  Reply   Trace   Private Reply  


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