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Health
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Title: Desk job workers face twice the risk of colon cancer
Source: [None]
URL Source: http://www.themedguru.com/20110420/ ... lon-cancer-study-86144434.html
Published: Apr 20, 2011
Author: by Dipankar Roy
Post Date: 2011-04-20 07:14:09 by Tatarewicz
Keywords: None
Views: 25
Comments: 1

People who believe they are comfortable with their desk jobs may have a reason to worry as findings by Australian researchers suggest long-term sedentary work may lead to an increased risk of chronic diseases.

Terry Boyle, a Ph.D. aspirant, and his colleague from the Western Australian Institute for Medical Research, University of Western Australia, observed a link between desk jobs and colorectal cancer [abnormal cells that divide without control, which can invade nearby tissues or spread through the bloodstream and lymphatic system to other parts of the body. ] , and found it to be independent of any recreational activity.

The two-year long study involving men and women aged 40-79 years living in Western Australia (WA) also observed the association in participants who were most recreationally active.

Researchers, however, found no link between desk jobs and the risk of proximal colon [The part of the large intestine that runs from the cecum to the rectum as a long hollow tube that serves to remove water from digested food and let the remaining material, solid waste called stool, move through it to the rectum and leave the body through the anus. ] cancer.

The researchers said, "Sedentary behavior appears to be a novel and important risk factor for many chronic diseases.”

Population-based study The population-based case-control study involved a total of 918 patients and 1021 control participants selected from the WA Cancer Registry.

Researchers collected data related on participants’ lifestyle, physical activity, and lifetime job history.

Jobs were categorized into five groups varying from sedentary (such as bookkeepers, computing professionals), light (teachers, hairdressers), medium (mechanics, nurses), heavy (plumbers, farmers) and very heavy (miners, fire-fighters).

The researchers found that participants who spent 10 or more years in sedentary work had almost twice the risk of distal colon cancer and a 44 percent increased risk of rectal cancer compared with those who did not had a sedentary work.

Lifestyle factors play major role While proposing an increased blood glucose levels and decreased insulin [a hormone produced by the pancreas. Insulin affects the amount of glucose absorbed by the liver.] resistance as the reason for the observation, the researchers said, “Our finding that sedentary work is associated with the risk of distal colon cancer but not proximal colon cancer adds to the evidence suggesting that lifestyle factors may play a larger role in distal colon carcinogenesis than in proximal colon carcinogenesis.”

“There is no clear mechanistic explanation, however, for why sedentary behaviour would increase the risk of distal colon and rectal cancers, but not proximal colon cancer,” they added.

“The findings of this study have occupational health implications, especially given that advances in technology have led to increasing amounts of sedentary behaviours at work and in other settings,” they said, advising on curbing the hours spent sitting.

The research has been published in the ‘American Journal of Epidemiology.’

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#1. To: Tatarewicz (#0)

I guess a pen ain't always lighter than a shovel.

Prefrontal Vortex  posted on  2011-04-20   11:49:03 ET  Reply   Untrace   Trace   Private Reply  


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