[Home]  [Headlines]  [Latest Articles]  [Latest Comments]  [Post]  [Sign-in]  [Mail]  [Setup]  [Help] 

Status: Not Logged In; Sign In

Fooling Us Badly With Psyops The Nobel Prize That Proved Einstein Wrong Put Castor Oil Here Before Bed – The Results After 7 Days Are Shocking Sounds Like They're Trying to Get Ghislaine Maxwell out of Prison Mississippi declared a public health emergency over its infant mortality rate (guess why) Andy Ngo: ANTIFA is a terrorist organization & Trump will need a lot of help to stop them America Is Reaching A Boiling Point The Pandemic Of Fake Psychiatric Diagnoses This Is How People Actually Use ChatGPT, According To New Research Texas Man Arrested for Threatening NYC's Mamdani Man puts down ABC's The View on air Strong 7.8 quake hits Russia's Kamchatka My Answer To a Liberal Professor. We both See Collapse But.. Cash Jordan: “Set Them Free”... Mob STORMS ICE HQ, Gets CRUSHED By ‘Deportation Battalion’’ Call The Exterminator: Signs Demanding Violence Against Republicans Posted In DC Crazy Conspiracy Theorist Asks Questions About Vaccines New owner of CBS coordinated with former Israeli military chief to counter the country's critics, BEST VIDEO - Questions Concerning Charlie Kirk, Douglas Macgregor - IT'S BEGUN - The People Are Rising Up! Marine Sniper: They're Lying About Charlie Kirk's Death and They Know It! Mike Johnson Holds 'Private Meeting' With Jewish Leaders, Pledges to Screen Out Anti-Israel GOP Candidates Jimmy Kimmel’s career over after ‘disgusting’ lies about Charlie Kirk shooter [Plus America's Homosexual-In-Chief checks-In, Clot-Shots, Iryna Zarutska and More!] 1200 Electric School Busses pulled from service due to fires. Is the Deep State Covering Up Charlie Kirk’s Murder? The FBI’s Bizarre Inconsistencies Exposed Local Governments Can Be Ignorant Pissers!! Cash Jordan: Gangs PLUNDER LA Mall... as California’s “NO JAILS” Strategy IMPLODES Margin Debt Tops Historic $1 Trillion, Your House Will Be Taken Blindly Warns Dohmen Tucker Carlson LIVE: America After Charlie Kirk Charlie Kirk allegedly recently refused $150 million from Israel to take more pro Israel stances "NATO just declared War on Russia!"Co; Douglas Macgregor

Health
See other Health Articles

Title: How a Protein Meal Tells Your Brain You're Full
Source: [None]
URL Source: http://www.sciencedaily.com/releases/2012/07/120705172041.htm
Published: Jul 5, 2012
Author: staff
Post Date: 2012-07-06 04:12:20 by Tatarewicz
Keywords: None
Views: 15

ScienceDaily (July 5, 2012) — Feeling full involves more than just the uncomfortable sensation that your waistband is getting tight. Investigators reporting online on July 5th in the Cell Press journal Cell have now mapped out the signals that travel between your gut and your brain to generate the feeling of satiety after eating a protein-rich meal. Understanding this back and forth loop between the brain and gut may pave the way for future approaches in the treatment and/or prevention of obesity.

Food intake can be modulated through mu-opioid receptors (MORs, which also bind morphine) on nerves found in the walls of the portal vein, the major blood vessel that drains blood from the gut. Specifically, stimulating the receptors enhances food intake, while blocking them suppresses intake. Investigators have now found that peptides, the products of digested dietary proteins, block MORs, curbing appetite. The peptides send signals to the brain that are then transmitted back to the gut to stimulate the intestine to release glucose, suppressing the desire to eat.

Mice that were genetically engineered to lack MORs did not carry out this release of glucose, nor did they show signs of 'feeling full', after eating high-protein foods. Giving them MOR stimulators or inhibitors did not affect their food intake, unlike normal mice.

Because MORs are also present in the neurons lining the walls of the portal vein in humans, the mechanisms uncovered here may also take place in people.

"These findings explain the satiety effect of dietary protein, which is a long-known but unexplained phenomenon," says senior author Dr. Gilles Mithieux of the Université de Lyon, in France. "They provide a novel understanding of the control of food intake and of hunger sensations, which may offer novel approaches to treat obesity in the future," he adds.

Post Comment   Private Reply   Ignore Thread  

[Home]  [Headlines]  [Latest Articles]  [Latest Comments]  [Post]  [Sign-in]  [Mail]  [Setup]  [Help]