[Home]  [Headlines]  [Latest Articles]  [Latest Comments]  [Post]  [Sign-in]  [Mail]  [Setup]  [Help]  [Register] 

Status: Not Logged In; Sign In

45 Funny Cybertruck Memes So Good, Even Elon Might Crack A Smile Possible Trump Rally Attack - Serious Injuries Reported BULLETIN: ISRAEL IS ENTERING **** UKRAINE **** WAR ! Missile Defenses in Kiev ! ATF TO USE 2ND TRUMP ATTACK TO JUSTIFY NEW GUN CONTROL... An EMP Attack on the U.S. Power Grids and Critical National Infrastructure New York Residents Beg Trump to Come Back, Solve Out-of-Control Illegal Immigration Chicago Teachers Confess They Were told to Give Illegals Passing Grades Am I Racist? Reviewed by a BLACK MAN Ukraine and Israel Following the Same Playbook, But Uncle Sam Doesn't Want to Play "The Diddy indictment is PROTECTING the highest people in power" Ian Carroll The White House just held its first cabinet meeting in almost a year. Guess who was running it. The Democrats' War On America, Part One: What "Saving Our Democracy" Really Means New York's MTA Proposes $65.4 Billion In Upgrades With Cash It Doesn't Have More than 100 killed or missing as Sinaloa Cartel war rages in Mexico New York state reports 1st human case of EEE in nearly a decade Oktoberfest tightens security after a deadly knife attack in western Germany Wild Walrus Just Wanted to Take A Summer Vacation Across Europe [Video] 'Days of democracy are GONE' seethes Neil Oliver as 'JAIL' awaits Brits DARING to speak up Police robot dodges a bullet, teargasses a man, and pins him to the ground during a standoff in Texas Julian Assange EXPOSED Howling mad! Fury as school allows pupil suffering from 'species dysphoria' to identify as a WOLF "I Thank God": Heroic Woman Saves Arkansas Trooper From Attack By Drunk Illegal Alien Taxpayers Left In The Dust On Policy For Trans Inmates In Minnesota Progressive Policy Backfire Turns Liberals Into Gun Owners PURE EVIL: Israel booby-trapped CHILDRENS TOYS with explosives to kill Lebanese children These Are The World's Most Reliable Car Brands Swing State Renters Earn 17% Less Than Needed To Afford A Typical Apartment Fort Wayne man faces charges for keeping over 10 lbs of fentanyl in Airbnb 🚨 Secret Service Announces EMERGENCY LIVE Trump Assassination Press Conference | LIVE Right Now [Livestream in progress] More Political Perverts, Kamala's Cringe-fest On Oprah, And A Great Moment For Trump

Science/Tech
See other Science/Tech Articles

Title: Chinese biologists find new method to improve cell reprogramming efficiency
Source: [None]
URL Source: [None]
Published: May 27, 2013
Author: staff
Post Date: 2013-05-27 01:34:21 by Tatarewicz
Keywords: None
Views: 19

LONDON, May 26 (Xinhua) -- Sequential introduction of the proteins known to reprogram cells could improve the efficiency of cell reprogramming, according to a new study reported in Nature Cell Biology on Sunday.

Currently, researchers use simultaneous introduction method in cell reprogramming, which introduces the proteins to reprogram cells back to a pluripotent, embryonic-like state.

Chinese stem-cell biologist Pei Duanqing and colleagues from Chinese Academy of Sciences reported that the sequential introduction of reprogramming proteins outperforms simultaneous introduction.

According to the report, sequential introduction leads to a greater number of cells being reprogrammed than traditional method, and the increase in efficiency was observed both for mouse and human differentiated cells.

The successive expression of reprogramming factors promotes the cells to adopt mesenchymal characteristics before going through an epithelial state and finally reaching pluripotency.

This discovery provided a technique for further optimizing the reprogramming of somatic cells to induced pluripotent stem cells, researchers said.

"Improving the efficiency of reprogramming somatic cells to induced pluripotent stem cells is highly beneficial to researchers," Professor Pei told Xinhua.

"The researchers could use reprogrammed cells to analyze how defects characteristic of a variety of diseases appear in cells in the laboratory or to test the potential of drugs to cure these defects," said Pei. Editor: Mengjie

Poster Comment:

Mesenchymal stem cells, or MSCs, are multipotent stromal cells that can differentiate into a variety of cell types,[1] including: osteoblasts (bone cells),[2] chondrocytes (cartilage cells),[3] and adipocytes (fat cells). This phenomenon has been documented in specific cells and tissues in living animals and their counterparts growing in tissue culture.

Definition of Human pluripotent stem cell Human pluripotent stem cell: One of the "cells that are self-replicating, are derived from human embryos or human fetal tissue, and are known to develop into cells and tissues of the three primary germ layers. Although human pluripotent stem cells may be derived from embryos or fetal tissue, such stem cells are not themselves embryos." (From the National Institutes of Health Guidelines for Research Using Human Pluripotent Stem Cells.) "Self-replicating" means the cell can divide and to form cells indistinguishable from it. The "three primary germ layers" -- called the ectoderm, mesoderm, and endoderm -- are the primary layers of cells in the embryo from which all tissues and organs develop. Human pluripotent stem cells are also known as human embryonic stem cells.

Post Comment   Private Reply   Ignore Thread  

[Home]  [Headlines]  [Latest Articles]  [Latest Comments]  [Post]  [Sign-in]  [Mail]  [Setup]  [Help]  [Register]