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Health See other Health Articles Title: How Agricultural Chemicals and Hospital Stays Contribute to Alzheimer’s How Agricultural Chemicals and Hospital Stays Contribute to Alzheimer’s October 17, 2013 | 154,108 views By Dr. Mercola It is projected that Alzheimer's will affect one in four Americans in the next two decades, rivaling the current prevalence of obesity and diabetes. At present, the disease afflicts about 5.4 million Americans. One of the potential reasons for the skyrocketing increase in Alzheimer’s may be related to rising glyphosate residues in our food supply. Glyphosate is the active ingredient in Monsanto’s herbicide Roundup, used in ever-increasing amounts on genetically engineered (GE) crops. Glyphosate is a potent mineral chelator, binding up minerals like zinc and manganese from being used by the plant, or anyone who eats the plant since it is impossible to wash off glyphosate as it becomes integrated into all the plant cells. Zinc deficiency in turn, is thought to contribute to diseases such as Alzheimer’s and Parkinson’s. There is still no known cure for Alzheimer’s, and very few treatments. Alzheimer's drugs are often of little to no benefit, which underscores the importance of prevention. Fortunately, there’s compelling research showing that your brain has great plasticity and capacity for regeneration, which you control through your diet and lifestyle choices. Avoiding gluten appears to be of critical importance, as is making sure you’re getting plenty of healthful fats (including demonized saturated fats). Fasting also has a remarkably beneficial influence on your brain health. At the end of this article, I share my best tips for avoiding this devastating brain disorder. How Zinc Deficiency May Contribute to Alzheimer’s According to researchers at the University of Wisconsin-Madison,1 zinc deficiency may play an important role in the development of Alzheimer’s. The disease has already been linked to accumulation of clumps of defective proteins in your brain, and zinc, it turns out, is critical for preventing such accumulation. As reported by the featured article:2 “With proteins, shape is everything. The correct shape allows some proteins to ferry atoms or molecules about a cell, others to provide essential cellular scaffolding or identify invading bacteria for attack. When proteins lose their shape due to high temperature or chemical damage, they stop working and can clump together - a hallmark of Parkinson's and Alzheimer's. The UW researchers have discovered another stress that decreases protein stability and causes clumping: a shortage of zinc, an essential metal nutrient. Zinc ions play a key role in creating and holding proteins in the correct shape.” As mentioned earlier, modern agricultural chemicals may be a significant driver of this disease, as many herbicides and pesticides are potent chelators. In fact, glyphosate was initially patented as a mineral chelator. Chelators immobilize nutrients, by binding them so they’re not physiologically available for your body. They do this by forming a barrier around specific nutrients, effectively preventing them from being utilized properly by either soil microbes, plants, animals or humans. Even if the mineral is present in the plant, if it’s chelated with glyphosate, those minerals will not be physiologically available for your body to use. This concept has been discussed at some depth by Dr. Don Huber, an award-winning, internationally recognized scientist and professor of plant pathology at Purdue University for the past 35 years. His agriculture research is focused on the epidemiology and control of soil-borne plant pathogens, with specific emphasis on microbial ecology, cultural and biological controls, and the physiology of host-parasite relationships. Glyphosate in particular is a significant threat to health as it’s one of the most widely used herbicides in the world. We are currently using about 880 million pounds—that’s nearly ONE BILLION pounds—of glyphosate annually on food crops grown worldwide. GE plants in particular are being sprayed with ever increasing amounts of Roundup as weeds are becoming increasingly resistant to the herbicide. As a result, genetically engineered grains tend to have the highest levels of glyphosate residue. In one test, GE corn was found to contain 13 ppm of glyphosate, compared to zero in non-GE corn. According to Dr. Huber, the nutritional efficiency of genetically engineered (GE) plants is profoundly compromised. Micronutrients such as iron, manganese and zinc can be reduced by as much as 80-90 percent in GE plants! Naturally, health effects are bound to occur if you’re consistently eating foods from which your body cannot extract critical nutrients and minerals. Glyphosate Appears May Be One of the Most Potent Drivers of Modern Diseases As Dr. Seneff and Samsel reveal in a recent study conducted at the Massachusetts Institute of Technology, glyphosate is probably the most harmful chronic toxin we’ve ever encountered, and could possibly be the most important factor in the development of multiple chronic diseases and conditions that have become prevalent in Westernized societies today—including Alzheimer’s, autism, Crohn’s disease, gluten intolerance, leaky gut and many others. Besides chelating micronutrients, glyphosate is also patented as an antibiotic. And like all antibiotics, it indiscriminately kills both detrimental and beneficial soil- and human gut bacteria. Your gut bacteria are in fact a key component of glyphosate’s mechanism of harm, as microbes have the pathway used by glyphosate to kill weeds, called the shikimate pathway. For every cell in your body, you have 10 microbes of various kinds, and all of them have the shikimate pathway, so they will all respond to the presence of glyphosate, which causes extreme disruption of the microbe’s function and lifecycle. What’s worse, glyphosate preferentially affects beneficial bacteria, allowing pathogens to overgrow and take over. At that point, your body also has to contend with the toxins produced by the pathogens. Once the chronic inflammation sets in, you’re well on your way toward chronic and potentially debilitating disease. It’s well worth noting that, on May 1, 2013, the US Environmental Protection Agency (EPA) doubled the amount of glyphosate allowed in food... Soybean oil may now contain as much as 40 parts per million (ppm) of glyphosate. Meanwhile, research by Dr. Monika Krueger at Leipzig University shows that a tenth of a part per million is all that it takes to kill your Lactobacillus, Bifidobacterium, and Enterococcus faecalis. So soybean oil is now allowed to contain a whopping 400 times the known limit at which it can impact your health. From my perspective, there’s little doubt that if you want to protect your brain and physical health, ridding your diet of foods that have been genetically modified (GMO’s) is a critical step. Ideally, you’d want to eat a primarily organic diet, in order to avoid agricultural chemicals entirely. ICU Stays Lead to Symptoms of Alzheimer’s in 1/3 of Patients In related news, new research3 shows that a stay in an intensive care unit (ICU) frequently results in symptoms of dementia in patients that have no cognitive problems prior to being admitted. In many, cognitive problems were found to persist for more than a year after being discharged from the hospital. Incredibly, 75 percent of ICU patients experienced delirium and left the hospital with symptoms of cognitive problems; one in three exhibited symptoms seen in Alzheimer’s patients. Dr. Wes Ely, a professor of medicine and critical care at Vanderbilt University Medical Center in Nashville told CBS News:4 “We knew that something was going wrong with people's brains when they were getting out of medical and surgical ICUs but we didn't understand to what degree their brains were being disabled and then having to live with that throughout their life. So, we set out to define exactly what was going on with the survivors of critical care in terms of brain function." One major factor that appears to contribute to this is the administration of sedatives, which can increase your risk of delirium, and subsequent longer-term cognitive problems. Interestingly, this phenomenon is not restricted to the elderly. Healthy people in their 30s and 40s also developed cognitive problems after a stay in the ICU. As reported in the featured article: “[Dr. Ely] thinks more needs to be done to keep patients in the ICU alert, awake and walking around if possible to reduce their odds of developing delirium. Exercising your brain with puzzles and games like Sudoku and Scrabble while in the ICU may also boost brain function. Monitoring how much patients sleep may also improve outcomes, since beepers, lights and staffers taking X-rays or blood tests may prevent someone in the ICU from getting adequate rest. ... In an accompanying editorial published in the same journal issue, researchers at the University of Toronto pointed out that not all patients had delirium, and some of the patients with cognitive problems at three months showed improvement by 12 months. Still, the study "unequivocally" showed that cognitive impairments in these patients is a public health concern.” This is a Flash-based video and may not be viewable on mobile devices. General Anesthesia Could Increase Risk of Dementia in Elderly by 35 Percent Related research suggests that being exposed to general anesthesia can increase the risk of dementia in the elderly by as much as 35 percent. The research was presented at this year’s annual congress of the European Society of Anesthesiology (ESA). As reported by Medical News Today:5 “Postoperative cognitive dysfunction, or POCD, could be associated with dementia several years later. POCD is a common complication in elderly patients after major surgery. It has been proposed that there is an association between POCD and the development of dementia due to a common pathological mechanism through the amyloid ² peptide. Several experimental studies suggest that some anesthetics could promote inflammation of neural tissues leading to POCD and/or Alzheimer's disease (AD) precursors including ²-amyloid plaques and neurofibrillary tangles.” In this study, participants aged 65 and over were followed for a total of 10 years. Participants exposed to at least one general anesthetic over the follow-up had a 35 percent increased risk of developing a dementia compared to those who were not exposed to anesthesia. According to lead researcher Dr. Francois Sztark:6 "These results are in favor of an increased risk for dementia several years after general anesthesia. Recognition of POCD is essential in the perioperative management of elderly patients. A long-term follow-up of these patients should be planned." Tips for Maintaining Healthy Brain Function and Avoiding Alzheimer's Disease The beauty of following my optimized nutrition plan is that it helps prevent and treat virtually ALL chronic degenerative diseases, including Alzheimer’s disease. Remember, while memory loss is indeed common among Westerners, it is NOT a "normal" part of aging, and cognitive changes are by no means inevitable. As explained by neurologist Dr. David Perlmutter, Alzheimer’s is a disease predicated primarily on lifestyle choices; the two main culprits being excessive sugar and gluten consumption. Another major factor is the development and increased consumption of genetically engineered (GE) grains, which are now pervasive in most processed foods sold in the US. His book, Grain Brain, provides a powerful argument for eliminating grains from your diet. Knowing that it is a preventable disease puts the power into your hands. People who experience very little decline in their cognitive function up until their deaths have been found (post-mortem) to be free of brain lesions, showing that it's entirely possible to prevent the damage from occurring in the first place… and one of the best ways to do this is by leading a healthy lifestyle. Poster Comment: When I worked for the State of Illinois, the joke going around went like this, "Do you know Al?" They would say, 'Al who?" The reply was, "Oh, you too, huh?" LOL Post Comment Private Reply Ignore Thread
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