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Health See other Health Articles Title: Celldex vaccine helps brain cancer patients live longer: study Yahoo... (Reuters) - Adding an experimental Celldex Therapeutics Inc vaccine that enlists the immune system to fight cancer to standard therapy helped patients with the deadliest type of brain cancer live longer, according to data from a midstage trial presented on Sunday. In the trial of 73 patients whose glioblastoma multiforme (GBM) had recurred after prior therapy, 30 percent of those given Celldex's Rintega along with Roche Holding's Avastin were alive after 18 months versus 15 percent of those who received only Avastin. "We are observing an extremely rare overall survival advantage that is now translating into long-term survival for a number of patients," said Dr. David Reardon, the trial's lead investigator, who presented the results at the American Society of Clinical Oncology meeting in Chicago. Celldex said it is in discussions with regulators on finding a pathway to approval. "We certainly think the data is good enough to justify accelerated approval," said Celldex Chief Medical Officer Thomas Davis. Rintega received breakthrough designation from the U.S. Food and Drug Administration, which is given to therapies seen as a potential advance in serious or life-threatening diseases. There is no cure for GBM, in which highly malignant brain tumors overpower healthy cells by consuming space, blood and nutrients in the brain. About 9,000 new cases are diagnosed every year in the United States. GBM tumors tend to become resistant to initial treatment relatively quickly. For newly diagnosed patients, the median survival rate is about 14 or 15 months if given standard chemotherapy treatment, such as Merck & Co's Temodar, explained Reardon, a neuro-oncology specialist expert from Dana-Farber Cancer Institute in Boston. Rintega belongs to an emerging class of drugs that spur the immune system to recognize and attack cancer. It targets tumors that carry a genetic mutation found in about a third of all glioblastoma cases. That amounts to roughly 4,000 patients in the United States. The vaccine was associated with a notable decrease in the need for steroids, and the numerous side effects associated with their use, researchers said. Data from a late-stage trial in newly diagnosed patients is expected in the next couple of months, Celldex Chief Executive Anthony Marucci said. Oppenheimer & Co analyst Christopher Marai forecast annual global Rintega sales reaching about $400 million for recurrent patients. If newly diagnosed patients were included, the figure would likely climb to $1 billion, he said. (Reporting by Natalie Grover in Bengaluru; Editing by Bill Berkrot and James Dalgleish, Ralph Boulton) Cancer treatments got gentler, yet kids' survival improved CHICAGO (AP) — The move to make cancer treatments gentler for children has paid a double dividend: More kids are surviving than ever before, and without the long-term complications that doomed many of their peers a generation ago, new research shows. Immunotherapy combo packs punch against melanoma Immunotherapy, which harnesses the power of the immune system in order to attack cancer, is more potent against melanoma when two agents are combined, but side effects rise too, researchers said Sunday. Findings of a randomized phase III trial compared nivolumab (Opdivo) alone or in combination… AFP Relax News Related Stories Merck immunotherapy appears effective in head and neck cancer: study Reuters More cancer success with drugs that enlist immune system Associated Press Roche immunotherapy improves lung cancer survival Reuters Bristol's Opdivo cuts risk of lung cancer death for some Reuters New drugs from Bristol, Merck at forefront of cancer meeting Reuters Poster Comment: John Man, I think Yahoo is the main purveyor of Big Pharma bull chit, now. Everyday, more articles appear touting this or that new med that lets dying patients hang on long enough for the BCM to drain their bank accounts. There is no cure for the above cited brain cancer because the BCM does not give research grants to those actively seeking 100% effective surgical removal procedures. There is no money, in the long-term, for the BCM, if a given procedure absolutely removes a cancer. That is why these shrinkage and containment meds are so great for the BCM's foul subterfuge: They give a little hope for another (miserable) day, thus easing more money from the dying.4-3 R Tumeric and Beta Glucan are 100x more effective and very safe compared to Big Pharma drugs. Joe Wow. Now pharma has found a new way to push their vaccine poisons. On DYING PATIENTS. They do the same thing to folks who show up at the hospital with kidney failure. Give them a fing shot that sends them into WORSE health right when they need dire help now. Google Dr. Suzanne Humphries, Nephrologist to read more.-2 Hello For people interested in possible natural treatments for cancer or to possibly prevent a recurrence they may like to check out Salvestrols.(And not the discrediting Wikipedia article about Salvestrols. The Salvestrols used in Salvestrol platinum pills do not use resveratrol.) Professor Burke of Aberdeen University discovered that all cancer cells have CYP1B1 enzyme. Professor Potter at De Montfort University discovered natural compounds found in fruits vegetables and herbs that transform CYP1B1 enzyme into anti-cancer agents. He named them Salvestrols. Burke and Potter got together with Anthony Daniels and created Salvestrol supplements. Google 'salvestrol case studies' and google 'Salvestrol Platinum' pills. Salvestrols can be used alone or with surgery, radiation, or chemotherapy. For children under 12 they need to consult a physician first. Why hasn't anyone heard about this? This all goes back to the days of Rockefeller. The book Rockefellers Medicine Men by Richard Brown showed how in the early days of chemical medicine Rockefeller used his money and power to gain influence and control over universities and they even taught their doctors to ridicule and attempt to edge out any and all other medical competition not under their control. And it did not matter if the natural methods of healing worked. Hence the existance of Quackwatch and attitudes similar to them. Even wikipedia has bias since most of the references are from big phama funded studies. As for vitamin c the mayo clinic and nih studies were poorly done, but are still used as an example by big pharma shills to discredit orthomoloecular (vitamin therapy) so they can continue to get paid by duping people into buying the chemicals. Ofcourse the FDA and others have business ties with big pharma which also have lobbying powers to control the government laws. Chemical drug big pharma typically have more contacts and much more money to advertise for their drugs compared to natural healing arts. Independent scientists cannot afford large scale clinic trials which cost millions of dollars (or more). Only large pharma companies can afford the large clinical trials. The pharma companies will not invest into natural non patented herbs because only patented drugs give them the few years to make a profit and get back all the money that was invested into the large scale clinical trials. Mainstream medicine only takes seriously large scale clinical trials the can only be afforded by large pharma companies. Some more books: Rockefellers Medicine Men by Richard Brown, Salvestrols: Natures Defense Against Cancer by Schaefer and Primal Panacea by Levy MD Well the point I am trying to make is that it is not so black and white. Both the natural and chemical healing arts exist for cancer and it is up to each person to do their own research so they are not one sided to find out what is best for them becuase everyone is different and responds differently to different things.1-3 research69 It is insanity to say somebody, anybody is preventing cures from coming to the market. If that were true, we would not have a vaccine for polio, for example. Think of all the money this cost the makers of "iron lungs". There is a cure for "gastro intestinal stromal cancer" or GIST. Tell me how that made it to market. If that thinking were true, Dr. Larry Einhorn at Indiana University Medical School would not have developed a CURE for testicular cancer. Post Comment Private Reply Ignore Thread Top • Page Up • Full Thread • Page Down • Bottom/Latest
#1. To: Tatarewicz (#0)
We've got to find out what causes horrible conditions like this. I guess smoking cigarettes increases the chances of cancer across the board. MSG burns holes in the brain but I don't remember it ever being implicated in the big C?
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