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Health See other Health Articles Title: Shorter Telomeres Seen in Heavy Teens With High Salt Intake Shorter Telomeres Seen in Heavy Teens With High Salt Intake By Anne Harding June 04, 2015 Editors' Recommendations Medscape... NEW YORK (Reuters Health) - Overweight and obese adolescents with a high sodium intake have shorter leukocyte telomeres than their peers who consume less sodium, new findings show. And more than 80% of the teens in the study had sodium intakes that exceeded the 2,300 mg limit recommended in the Dietary Guidelines for Americans, Dr. Haidong Zhu of the Georgia Prevention Institute at the Medical College of Georgia in Augusta, the first author of the new study, told Reuters Health. Based on the findings and other research on sodium's health effects, Dr. Zhu said, pediatricians should begin recommending that their patients lower their sodium intake. The findings were published online April 14 in the International Journal of Obesity. In previous research, Dr. Zhu and her team found that adolescents consumed excessive amounts of sodium, and that high sodium consumption was linked to more inflammation. Given that inflammation can reduce telomere length, they investigated whether sodium intake would be associated with telomere shortening in 766 14- to 18-year-olds, half of whom were female, and 49% of whom were African American. Study participants reported their dietary sodium intake in seven different 24-hour dietary recalls. The researchers measured leukocyte telomere length (LTL), which is often used in epidemiologic studies and correlates well with telomere length in cells from other types of tissue. Then they divided the adolescents into groups with high and low sodium intake, based on the median intake of 3,281 mg per day. The low-sodium group consumed a mean 2,388 mg of sodium daily, while the mean daily intake for the high-sodium group was 4,142 mg. Overall, and among the normal-weight teens, there was no association between LTL and sodium intake. But teens who consumed more sodium were more likely to be obese. And among the overweight and obese study participants, those in the high sodium intake group had shorter telomeres than overweight and obese teens in the low sodium group (p=0.04). The findings suggest that obesity and sodium intake are "additive and synergistic," Dr. Zhu said. She and her colleagues are now planning to examine the mechanisms underlying the relationship. "It could be due to inflammation, could be due to oxidative stress, or maybe some other process," the researcher said. "We cannot demonstrate a causal relationship because of the cross-sectional design of our study," she added. "Further research is definitely needed." SOURCE: http://bit.ly/1FtMTt9 Int J Obesity 2015. Poster Comment: Be interesting to see correlation between BMI and telomere length. Post Comment Private Reply Ignore Thread
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