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Health
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Title: New method of lowering blood sugar may help treat diabetes
Source: [None]
URL Source: [None]
Published: Sep 4, 2015
Author: Stephen Feller
Post Date: 2015-09-04 01:51:50 by Tatarewicz
Keywords: None
Views: 20

Rather than making the body more sensitive to insulin, the treatment lowers glucose production in the liver.

An experimental drug may offer type 2 diabetes patients a new way to control their blood sugar levels. Photo by Andrey_Popov/Shutterstock

ST. LOUIS, Sept. 3 (UPI) -- Researchers found a way to lower glucose production in the livers of mice, lowering levels of blood sugar in their bodies, potentially offering a new method of treatment for type 2 diabetes.

Many treatments for type 2 diabetes work by making the body more sensitive to insulin, which is the hormone that lowers blood sugar.

Previous research has shown that reducing glucose production by interfering with the function of a protein in the liver was possible, however the new study is the first to successfully do so, the researchers said.

"We think this strategy could lead to more effective drugs for type 2 diabetes," said Dr. Brian Finck, an associate professor of medicine at the University of Washington in St. Louis, in a press release. "A drug that shuts down glucose production has the potential to help millions of people affected by the most common form of diabetes."

Using an experimental compound called MSDC-0602 in mice, researchers showed that inhibiting a protein that helps to transport pyruvate in the bloodstream into mitochondria, the part of a cell that makes its energy.

Researchers think that preventing the production glucose could provide a better way of treating diabetes, as well as helping patients who have nonalcoholic fatty liver disease.

The study is published in Cell Metabolism. Like Us on Facebook for more stories from UPI.com

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