The results of the study found a dose-dependent relationship between aspartame consumption and the destruction of neurotransmitters brain chemicals necessary for the function of neurons. Brain neurotransmitters levels (serotonin, GABA and dopamine) were reduced significantly compared with control, the study says. Furthermore, levels of brain antioxidants that protect brain tissue from oxidation damage often caused by chemical exposure were sharply depleted.
[D]ata obtained showed that antioxidant activities (SOD and GSH) were reduced significantly, the study reports.
The conclusion of the study found that, Consumption of [aspartame] for a long time increased oxidative stress in brain tissue and disruption in neurotransmitters that affect physiological functions.