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Title: Plants are better than chemicals at stopping cancer
Source: [None]
URL Source: https://www.naturalnews.com/2019-07 ... uppress-cancer-stem-cells.html
Published: Jul 17, 2019
Author: staff
Post Date: 2019-07-17 13:41:00 by Horse
Keywords: None
Views: 300
Comments: 2

Plants are better than chemicals at stopping cancer: Pomegranates suppress cancer stem cells

Plants are proving to be better-equipped for dealing with cancer than modern pharmaceuticals. According to numerous studies, certain plants possess powerful chemicals that can do what conventional cancer treatments cannot: stop drug-resistant cancer stem cells. In a recent study published in Nutrition and Cancer, researchers from the University at Albany in New York revealed that pomegranates can be used in the prevention of breast cancer due to their ability to suppress cancer stem cells, which have become important targets of cancer therapy.

What are cancer stem cells?

Cancer stem cells refer to a small subpopulation of cells that can be found in tumors. As their name implies, cancer stem cells are capable of self-renewal and of transforming into any cell type. But what makes these cells dangerous is that they also have the same characteristics as cancer cells. Cancer stem cells are responsible not just for the development of tumors, but also for their progression, metastasis, and drug resistance. Cancer stem cells are not affected by chemotherapy and radiotherapy; in fact, some studies have reported that these treatments actually increase their number and malignancy.

The existence of cancer stem cells was a random discovery. Researchers were investigating the cause of a common form of blood cell cancer known as acute myeloid leukemia (AML) when they noticed a small fraction of the cell population that was different from the rest. These cells were still capable of dividing while the majority of the leukemic cells had already lost this ability. When they transferred some of these curious cells to a mouse, they initiated a new incidence of leukemia. The cells also showed resistance to chemotherapy and rapidly replenished the leukemic cell population right after therapy. This caused the recurrence of AML.

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Today, researchers know these cells as cancer stem cells. They also know that these cells have the same DNA mutations as ordinary cancer cells but behave differently due to their stem cell-like nature. As for the origin of these cells, researchers believe they are most likely the product of cell reprogramming, which has been observed in a variety of tumors. However, the mechanisms that drive this process are still unclear, and research on this subject is still ongoing.

Pomegranate extracts can alter the properties of breast cancer stem cells

The pomegranate plant (Punica granatum) is a fruit-bearing shrub native to Asian countries. It has been cultivated in the Mediterranean region since ancient times and is widely known for its fruit. The plant has attracted scientific interest for decades due to its medicinal properties, its history as a natural remedy, and its effectiveness against various pathogens. According to studies, nearly every part of the plant possesses antimicrobial, antioxidant, and anti-inflammatory properties. Pomegranates are also rich in beneficial compounds, such as ellagic acid, anthocyanins, punicalagin, and other hydrolyzable tannins. Pomegranate juice, peel, and oil are known for their anti-cancer activities.

For their study, the American researchers investigated the effects of pomegranate extract on two different breast cancer cell lines. They took particular note of the cells’ ability to form mammospheres or clumps of mammary gland cells – a hallmark of breast cancer stem cells. They reported that pomegranate extract reduced the formation of mammospheres in both breast cancer cell lines, suggesting that it can affect the ability of cancer stem cells to self-renew. When the researchers incubated mammospheres with the pomegranate extract, they observed that the cells broke formation and became adherent cultures. This suggested that the extract can cause cancer stem cells to differentiate into a specific mature cell type. Differentiation robs stem cells of their ability to proliferate rapidly and renew themselves.

The researchers also tested the effects of pomegranate extracts on epithelial-to-mesenchymal transition (EMT), a reprogramming process associated with the formation of cancer stem cells and the maintenance of their characteristics. The researchers reported that pomegranate extract reduced the ability of breast cancer stem cells to migrate. It also reduced the expression of genes involved in EMT, including a transcription factor that induces EMT. Based on these findings, the researchers concluded that the anti-tumor activity of pomegranate is due in part to its ability to stop EMT from happening. Because of this, they believe that pomegranates can be used in the prevention of breast cancer.


Poster Comment:

Apples and a mixture of turmeric with black pepper are the two most highly rated plants for preventing cancer.

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#1. To: Horse (#0)

God's medicines, not man's poisons.

“The most dangerous man to any government is the man who is able to think things out... without regard to the prevailing superstitions and taboos. Almost inevitably he comes to the conclusion that the government he lives under is dishonest, insane, intolerable.” ~ H. L. Mencken

Lod  posted on  2019-07-17   18:13:25 ET  Reply   Trace   Private Reply  


#2. To: Horse (#0)

Hope that applies to POM brand juice. Am drinking big bottles of it for my prostate -- which works wonders, BTW.

_____________________________________________________________

USA! USA! USA! Bringing you democracy, or else! there were strains of VD that were incurable, and they were first found in the Philippines and then transmitted to the Korean working girls via US military. The 'incurables' we were told were first taken back to a military hospital in the Philippines to quietly die. – 4um

NeoconsNailed  posted on  2019-07-17   19:44:49 ET  Reply   Trace   Private Reply  


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