Researchers at John Hopkins Childrens Center discovered from their lab experiments on mice that sulforaphane, a plant-derived chemical, known as a phytochemical, already found to have anti-cancer effects, can inhibit the replication of SARS-CoV-2, the coronavirus that causes COVID-19, and another human coronavirus in cells and mice. Sulforaphane can be found in cruciferous vegetables like broccoli sprouts, broccoli, cauliflower, kale, Brussels sprouts, cabbage, both red and white varieties, bok choy, watercress, arugula, also known as rocket.
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When the COVID-19 pandemic started, our multidisciplinary research teams switched our investigations of other viruses and bacteria to focus on a potential treatment for what was then a challenging new virus for us, according to Childrens Center microbiologist and senior author of the paper Lori Jones-Brando, Ph.D.
I was screening multiple compounds for anti-coronavirus activity and decided to try sulforaphane since it has shown modest activity against other microbial agents that we study, she added.
What we found is that sulforaphane is antiviral against HCoV-OC43 and SARS-CoV-2 coronaviruses while also helping control the immune response, Ordonez said.
This multifunctional activity makes it an interesting compound to use against these viral infections, as well as those caused by other human coronaviruses, he added.
Poster Comment:
Also works against cancer. It is anti-aging. Dr Jordan Patrick recommends it as a sprout.