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Health
See other Health Articles

Title: Jewish Genetic Diseases
Source: Manornet.com
URL Source: http://www.mazornet.com/genetics/index.asp
Published: Apr 14, 2007
Author: Various
Post Date: 2007-04-14 11:50:26 by YertleTurtle
Keywords: None
Views: 2061
Comments: 27

The first step towards unraveling the mysteries behind genetic disorders is to find the problem genes. Many defective genes have been identified and work is ongoing to discover feasible methods for "cures". While investigations of genetic treatments continue, people are in a position to begin using the current facts for their benefit.

There are nearly 4,000 genetic diseases known that afflict the world’s population. However, in almost every ethnic, racial, or demographic group, certain genetic diseases occur at higher frequencies among their members than in the general population. Such is the case for the Jewish people.

The genetic diseases described on Mazornet's Jewish Diseases are disorders which occur more frequently in individuals of Jewish ancestry. Most diseases are severely incapacitating and some are tragically debilitating, leading to death in infancy or early childhood. Tay-Sachs may be the most notorious of the lot, but other diseases, just as prevalent and just as devastating, shatter the lives of Jewish families.

Children and adults with a rare genetic disease have multiple needs to address: health concerns, primarily, but others as well. As a service to the global Jewish community, http://Mazornet.com is committed to gathering and compiling data about Jewish genetic disorders. More importantly, http://Mazornet.com’s mission is to serve as the ultimate information resource by surfacing areas of assistance online and in the real world. It is not http://Mazornet.com’s intent to choose resources, but rather to make support information and resources of any kind available to the people and to the families afflicted by these diseases. There is hope, and there is help.

Bloom's Syndrome

Breast and Ovarian Cancers

Canavan Disease

Crohn's Disease

Colon Cancer

Cystic Fibrosis

Fabry Disease

Familial Dysautonomia

Familial Mediterranean Fever

Fanconi Anemia

Gaucher Disease

Machado Joseph Disease

Mucolipidosis Type IV (ML4)

Neiman-Pick

Tay-Sachs Disease

Poster Comment:

Hey, leveller, hey Burkeman1, ya'll open your minds now, hear?

Post Comment   Private Reply   Ignore Thread  

#1. To: YertleTurtle (#0)

If you are either Jewish or Gentile and are worried about colon cancer please note that recent research posted here said that vitamin D3 reduces colon cancer.

The Truth of 911 Shall Set You Free From The Lie

Horse  posted on  2007-04-14   11:57:22 ET  Reply   Trace   Private Reply  

Here's a list of diseases known to afflict some Americans referred to as Melungeons.

http://www.melungeons.com/articles/augustfeature.htm

http://www.wired.com/science/discoveries/news/2002/06/53256

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   12:03:22 ET  Reply   Trace   Private Reply  

Melungeons.

Never heard of them before.

Strangely, my family, which is Celtic/German with some Cherokee, has no genetic diseases at all. Must be because we're all mutts. No purebreds at all, although I'm not sure what a "purebred" human might be.

"Be convinced that to be happy means to be free and that to be free means to be brave. Therefore do not take lightly the perils of war." -- Thucydides

YertleTurtle  posted on  2007-04-14   12:11:34 ET  Reply   Trace   Private Reply  

Open my mind about what? Sorry- I don't live in fear of the dreaded evil Jew like you- don't see his boney little cartoon finger behind every glass of spilled milk and cat up a tree.

Burkeman1  posted on  2007-04-14   12:24:30 ET  Reply   Trace   Private Reply  

Appalachia

Elvis may have been part Melungeon.

http://www.melungeon.org/

the Melungeons are traditionally identified by family names. A few of the surnames are associated with the Melungeons include Collins, Gibson, Goins, Mullins, and Bowlin. The Melungeons have historically been associated with the region along the Virginia-Tennessee border east of Cumberland Gap, with Newman’s Ridge in Hancock County, Tennessee, receiving most of the attention from journalists.

Some of these legends and theories have suggested descent from Spanish or Portuguese explorers, from the “Lost Colonists” of Roanoke Island, from shipwrecked sailors or pirates of various nationalities, from one of the Lost Tribes of Israel, or from ancient Phoenicians or Carthaginians. More recent theories have proposed that the Melungeons descended from Mediterranean or Middle Eastern ancestors.

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   12:31:14 ET  Reply   Trace   Private Reply  

I've read that the Melungeons were more than likely abandoned Turkish salior slaves from Drakes aramada in the late 1500's who intermarried with indians. The term "Mulengeon" itself is very similiar to a Turkish word meaning "cursed soul" or Moslem forced convert to Christianity- usaully as a result of slavery.

Burkeman1  posted on  2007-04-14   12:45:04 ET  Reply   Trace   Private Reply  

I believe that is the latest theory, previously Portuguese.

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   12:52:22 ET  Reply   Trace   Private Reply  

Yep- the previous theory was that they were shipwrecked Portugeese fisherman who for decades had known about North America before Columbus. But if so- they would have been in New England and Nova Scotia- because the Portugeese fishermen who ventured out that far- all went to the rich Grand Banks fishing grounds. They wouldn't have been ship wrecked that far south. And DNA testing has found a Turkish match.

Burkeman1  posted on  2007-04-14   12:56:57 ET  Reply   Trace   Private Reply  

Muslims ruled Spain and Portugal for centuries, so it still works. The DNA from these countries probably looks a lot like ME.

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   13:01:02 ET  Reply   Trace   Private Reply  

Spain and Portugal were conquered by Moors- Berbers - a mixture of North Africans and Arabs. They weren't Turks.

Burkeman1  posted on  2007-04-14   13:12:38 ET  Reply   Trace   Private Reply  

True, but where did the Tunisians originate?

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   13:16:49 ET  Reply   Trace   Private Reply  

Melungeons

The Melungeons are Turks is BULLSHIT! Those that push this theory are among a growing group of those American who wish they had an 'exotic' (i.e. non Anglo- Scots Irish) ethnicity so they can then join up in ethnocentric groups because they may be jealous at say Italian-America ethnic identities, etc. In an age of hyphenated Americans they feel left out and want to become hyphenated Americans as well. Such people then are funded by overseas nations like Turkey in search of American allies to work on the US Congress as a lobby group.

The Melungeon Mystery Solved

A Scientific Researcher's View

By James S. Elder

Young Turks….

Recently we have seen an over-abundance of newspaper and magazine articles suggesting that Melungeons may have Turkish roots. Such articles are inevitably of the interview type in which the reporter doesn't actually do any research himself but instead lets subjects ramble on about their latest supposed discovery. Journalists, with white space to fill, love every new conjecture. They neither know of the accuracy of these discoveries nor care if they are accurate. The comedian Carrot Top talking about physics would be as good as Einstein talking about physics for such "reporters". They are, after all, just reporting; and mindless babbling fills column space just as well as real research.

As far as I can determine, the Turkish Melungeon speculation seems to have started with Brent Kennedy and some apparently incorrect information. Kennedy is an entertaining man. I first heard him speak in Gate City, Virginia in October of 1995. According to his introduction at the talk, he holds a Ph. D. in Mass Communications from The University of Tennessee. He is certainly a good communicator. I still have an audiotape of that speech. He told the enthralled crowd about his brush with death from his Melungeon disease, let everyone hear the sound his Mediterranean teeth make when you pluck them with a fingernail, rubbed the bump on the back of his head, and spun a web of Turks stranded in 1586 by Sir Francis Drake at Roanoke Island who migrated to Hancock County and started the Melungeon race. It was an interesting, if not accurate, talk.

He says in the preface to his book that he is neither an historian nor an anthropologist. Nevertheless, he has managed to become a much-publicized name in Melungeon "research" over the past several years.. He certainly has charisma. Unfortunately, for his mass of partisans, his ideas don't appear to stand up to close, or even cursory, scientific examination.

Here's his basic story. According to his book, Kennedy became ill in 1988 with what eventually was diagnosed as erythema nodosum sarcoidosis. Kennedy and his wife went to the library and discovered sarcoidosis is "primarily of Middle Eastern and Mediterranean disease [sic], although it's not unknown among Irish and some Scandinavians as well…". Kennedy gets better, returns to his hometown in Virginia, talks to his family, and finds out his people were oppressed. He gets a research grant in 1995 from the Turkish government and goes to that country for a visit. He thinks that Turks and Melungeons look alike, eat alike, dance alike, dress alike, and have some similar sounding words. From all of this, he deduces that Melungeons are a mish-mash of people including Portuguese from Santa Elena, Dominicans, Jesuits, French Huguenots, Acadians, Drake's Turks and others who mysteriously decided to leave the Atlantic coast and go to the boonies, intermarry with Native Americans and become the Melungeons. He somehow divines "that the Turkish/Moorish element was at least in the beginning the predominant one…".

First of all, sarcoidosis is not predominantly a Middle Eastern or Mediterranean disease. Far from being "not unknown" among the Irish and Scandinavians, those populations, along with Germans and Puerto Ricans, have the highest incidence of the disease.

I examined information from a number of physicians who specialize in treating sarcoidosis as well as information found in standard medical literature. The literature and MDs' definitions and etiologies of sarcoidosis invariably followed that of the National Institutes of Health. The NIH says," Sarcoidosis was once considered a rare disease. We now know that it is a common chronic illness that appears all over the world… It occurs in all races and in both sexes. Nevertheless, the risk is greater if you are a young black adult, especially a black woman, or of Scandinavian, German, Irish, or Puerto Rican origin. No one knows why…No one knows what causes sarcoidosis… Sarcoidosis is currently thought to be associated with a abnormal immune response. Whether a foreign substance is the trigger is [sic] a chemical, drug, virus, or some other substance; how exactly the immune disturbance is caused are [sic] not known". The article these comments are taken from can be found at http://www.nlm .nih.gov/medlineplus/ency/article/000076.htm .

Simply put, no one knows what causes sarcoidosis. Suggestions have included a virus, a fungus, a bacillus, and even pine pollen. A genetic connection has been suggested but has not been proven by scientific study. It is much more prevalent among the Irish than the peoples of the Middle East. In my view, if sarcoidosis has a genetic link, it certainly seems that someone named Kennedy would be more likely to trace the disease to the Irish than to the Turks.

Kennedy suggests that the similar sound of some Middle Eastern words compared to American words support his conjecture that Melungeons have a Turkish connection. Alabama for instance, according to Kennedy, sounds like "Allah Bamya" meaning God's graveyard in Turkish. The fact is, we don't know exactly where the word Alabama came from. It was the name of a southern Indian tribe who lived in what is now central Alabama. The term first appears in the accounts of the Hernando de Soto expedition of 1540. It was written Alibamo by Garcillasso de la Vega, Alibamu by the Knight of Elvas, and Limamu by Rodrigo Ranjel.

How this term could somehow come from the Turks is "jest-a-bit" fuzzy in my old brain. One writer (not Kennedy) suggested that Turks are somehow cousins of Native Americans through some mysterious Asian connection. I can only surmise that, according to this reasoning, the early Neo-Indians must have brought a bunch of meaningless (to them) Turkish terms with them when crossing the Bering Strait land bridge during the Ice Age and mysteriously applied the terms centuries later to themselves. Or maybe Turks somehow came to the Americas before 1540, headed for the backwoods, met a tribe of Indians and mentioned their term meaning "God's graveyard". The Indians didn't speak Turkish but must have thought Allah Bamya sounded neat and immediately changed the name of the tribe from whatever they had been calling themselves to "Alabama". Maybe not….

I simply see no legitimate evidence suggesting that Melungeons are somehow of Turkish ancestry. Such "evidence" has turned out to be either incorrect or appears to be just wild speculation.

Conclusions

Solid genealogical study of Melungeon ancestry overwhelmingly leads to a simple conclusion. The primary genetic makeup of Melungeons - that which gives them their Melungeon physical characteristics - comes from certain Native American tribal genetic lines.

Hancock County historian and folklorist Bill Grohse, whose wife was a Mizer and a descendant of the Melungeon Collinses, in his papers and letters, wrote that Melungeons always said they were Indians.

Careful genealogical research, working backward from universally accepted Melungeons, shows their ancestral lines go back to Native Americans.

The Melungeon mystery has been solved through careful research. The truth may not be as exciting as having an unsolved conundrum but the truth is that Melungeons almost certainly are descendants of the intermarriage of Native Americans with old-world colonists.

This isn't an opinion. This is a scientific conclusion.

They aren't Portuguese. They aren't Turks. They are Native Americans.

"The desire to rule is the mother of heresies." -- St. John Chrysostom

Destro  posted on  2007-04-14   17:03:24 ET  Reply   Trace   Private Reply  

Native American is just part of their makeup, it has never been denied.

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   17:18:42 ET  Reply   Trace   Private Reply  

Native American is just part of their makeup, it has never been denied.

Listen to me - throw out your racial non scientific fantasies.

From the above article I linked:

The Melungeon mystery has been solved through careful research. The truth may not be as exciting as having an unsolved conundrum but the truth is that Melungeons almost certainly are descendants of the intermarriage of Native Americans with old-world colonists.

Not Tunisians, Not Arabs and Not Turks.

Scientific truth is boring and unsexy. Get used to it.

Never mention your pet theories on this again. Help end the chain of unscientific reasoning on this issue and the general acceptance of BS in this country as fact. Forget all you wrote on this subject and don't pass on the BS chain of thought you had previously mentioned.

"The desire to rule is the mother of heresies." -- St. John Chrysostom

Destro  posted on  2007-04-14   17:27:17 ET  Reply   Trace   Private Reply  

Why do you think your links are the only links?

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   17:38:49 ET  Reply   Trace   Private Reply  

Why do you think your links are the only links?

Links? Links are not evidence - science is evidence. If you can't tell the difference then I suggest you refrain from surfing the Internet - because a little knowledge can be a dangerous thing. I am tired of ethnic hucksters from the British Israelite cultists on down.

"The desire to rule is the mother of heresies." -- St. John Chrysostom

Destro  posted on  2007-04-14   17:54:44 ET  Reply   Trace   Private Reply  

http://www.wired.com/science/discoveries/news/2002/06/53256

http://www.melungeon.org/

I posted scientific evidence as well. You really are a pompous, arrogant little snit. But you knew that.

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   18:04:41 ET  Reply   Trace   Private Reply  

May I ask why after I posted a scientific debunking of this you persist in it? Does it turn you on to accept bullshit over science?

Those are not scientific articles you linked - just bozo journalism. The above article I linked be-dunks the rash of stories printed and why these stories got any press.

and as I showed in my link - the main disease that is linked to these people IS NOT A DESEASE EXCLUSIVE TO MEDITTERANIAN PEOPLE LIKE TURKS!

NIH says," Sarcoidosis was once considered a rare disease. We now know that it is a common chronic illness that appears all over the world… It occurs in all races and in both sexes. Nevertheless, the risk is greater if you are a young black adult, especially a black woman, or of Scandinavian, German, Irish, or Puerto Rican origin. No one knows why…No one knows what causes sarcoidosis…A genetic connection has been suggested but has not been proven by scientific study. It is much more prevalent among the Irish than the peoples of the Middle East. In my view, if sarcoidosis has a genetic link, it certainly seems that someone named Kennedy would be more likely to trace the disease to the Irish than to the Turks.

So why do you push the bullshit position? Stop it.

"The desire to rule is the mother of heresies." -- St. John Chrysostom

Destro  posted on  2007-04-14   18:13:48 ET  Reply   Trace   Private Reply  

You really are a pompous, arrogant little snit. But you knew that.

The article you posted from Wired titled: 'Tracing Heritage Through Disease'

The Wired article's thesis is debunked here: The Melungeon Mystery Solved Are you Diseased?

Hopefully, it is sufficient to say that in order to demonstrate that a disease is an indicator of Melungeon ancestry, one has to show that generations of universally accepted Melungeons had that disease. Historical records are devoid of any such suggestions. As far as I can determine, there is just no such evidence. In fact, examination of the records shows Melungeons to be remarkably healthy and long-lived..In all, I just don't find any credible evidence of 'Melungeon diseases".

"the nightmare of American hysteria, ignorance, arrogance, stupidity and belligerence" - Harold Pinter

"The desire to rule is the mother of heresies." -- St. John Chrysostom

Destro  posted on  2007-04-14   18:25:22 ET  Reply   Trace   Private Reply  

http://www.wired.com/science/discoveries/news/2002/06/53256

http://www.melungeon.org/

I posted these links before you posted your link, in posts #2 and #3.

Jones is about to announce DNA research results on FMF and the other rare diseases found in people of the southern Appalachian region. He hopes his research will increase awareness and encourage doctor education of these diseases, so no one will ever again have to wait 30 years for a diagnosis.

Diseases of the Melungeons include Behcet's Syndrome, Machado-Joseph Disease, Familial Mediterranean Fever, Sarcoidosis and thalassemia.

All of the diseases are associated with ethnicities not commonly found in Appalachia: Mediterranean, Jewish, Arab, Turkish and African.

The other link is to an organization by and for those of Melungeon heritage.

I ran across this group at http://www.rootsweb.com several years ago. The rare diseases shared by some with this distinct heritage brought them together, as well as oral tradition.

I have no horse in this race, and keep an open mind about who their ancestors are. As DNA testing progresses, I'm sure we'll learn more.

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   18:32:39 ET  Reply   Trace   Private Reply  

As DNA testing progresses, I'm sure we'll learn more.

DNA - Why it won't work

and

At the suggestion of N. Brent Kennedy, a DNA study on Melungeons was carried out in 2000 by Dr. Kevin Jones, using 130 hair and cheek cell samples. These samples were taken from subjects who were largely chosen by Kennedy himself as representative of Melungeon lines. McGowan (2003) describes Dr Jones' apparent frustration with the study, which caused disappointment among some observers. "...Jones concluded that the Melungeons are mostly Eurasian, a catchall category spanning people from Scandinavia to the Middle East. They are also a little bit black and a little bit American Indian."[40] This study has to date not been submitted to a peer-reviewed scientific journal, nor has a list of those contributing samples been published; thus, it is unclear to what extent the subjects were actually descendants of families historically designated as "Melungeon."

and

http://www.wired.com/medtech/health/news/2002/06/53165? currentPage=2

One skeptic is David Henige, an oral tradition and historical methodology expert at the University of Wisconsin at Madison. He calls Kennedy's book, which asserts that Melungeons may be of Turkish descent, "bad history."

"My objection to Brent Kennedy's book was that it was so ahistorical in its use of evidence," Henige said. "DNA testing might show that they are descended from Turks like he said, and that's fine -- if that's what it shows, that's what it shows. But I have no reason to expect it would."

European sequences are next to impossible to categorize according to country because Europeans have migrated quickly through the centuries. This historical intermingling of ethnicities has made modern European DNA an unidentifiable mishmash.

"The desire to rule is the mother of heresies." -- St. John Chrysostom

Destro  posted on  2007-04-14   18:42:56 ET  Reply   Trace   Private Reply  

More recently, Jack Goins has started a Melungeon DNA Project, with the goal of studying the ancestry of hypothesized Melungeon lines. Y chromosomal DNA testing [41] of male subjects with the Melungeon surnames Collins, Gibson, Goins, Bunch, Bolin, Goodman, Williams, Minor and Moore has revealed evidence of European and sub-Saharan African ancestry: Y haplogroups R1b, R1a, J2; and E3a, respectively.[42] One Goins line looks likely to be a variety of Y haplogroup L with roots in Portugal, Spain and Italy. Taken as a whole, such findings appear to verify the early designation of Melungeon ancestors as "mulattos."

You left out the rest of that wiki DNA section.

BTW, mulatto was always considered part of the tri-mix.

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   18:48:21 ET  Reply   Trace   Private Reply  

You left out the rest of that wiki DNA section.

I did not want to post the entire webpage. But the above sentence proves the original scientific review's point that I posted: The Melungeon mystery has been solved through careful research. The truth may not be as exciting as having an unsolved conundrum but the truth is that Melungeons almost certainly are descendants of the intermarriage of Native Americans with old-world colonists.

That would be "old-world colonists" "with roots in Portugal, Spain and Italy".

"The desire to rule is the mother of heresies." -- St. John Chrysostom

Destro  posted on  2007-04-14   18:53:02 ET  Reply   Trace   Private Reply  

with roots in Portugal, Spain and Italy.

Except they were not the groups that first colonized Virginia etc.

And, as noted at the beginning of this thread, Portuguese was the original theory.

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-14   18:56:38 ET  Reply   Trace   Private Reply  

Did you bother reading? You called me arrogant but you are as dumb as nails.

The sample selected for the DNA test was bogus - the guy Kenndy - an ethnic huckster - hand picked people he thinks are Melungeon. Therefore -once again for you slow readers - the DNA test in question is BULLSHIT. Even this bullshit DNA test indicated COMMON genetic traits among Europeans in any case (which is why I mentioned it - it disproved that huckster Kennedy's thesis with his own selected gene pool).

Now let it go and consider the matter over.

"The desire to rule is the mother of heresies." -- St. John Chrysostom

Destro  posted on  2007-04-15   5:31:14 ET  Reply   Trace   Private Reply  

More recently, Jack Goins has started a Melungeon DNA Project, with the goal of studying the ancestry of hypothesized Melungeon lines. Y chromosomal DNA testing [41] of male subjects with the Melungeon surnames Collins, Gibson, Goins, Bunch, Bolin, Goodman, Williams, Minor and Moore has revealed evidence of European and sub-Saharan African ancestry: Y haplogroups R1b, R1a, J2; and E3a, respectively.[42] One Goins line looks likely to be a variety of Y haplogroup L with roots in Portugal, Spain and Italy. Taken as a whole, such findings appear to verify the early designation of Melungeon ancestors as "mulattos."

Try taking your own advice it was not not Kennedy, but Goins who found the above results.

As I already pointed out it was some uncommon ailments shared by some of these descendants, along with oral tradition, that brought about these DNA studies.

Again, I have no personal stake in this history, but I stumbled across this bit of unique history and genealogy at http://www.rootsweb.com. I am open to what is discovered, but take all the research into consideration, not just one link (which was my original criticism of your posting on this subject).

You seem to have some predisposed opinions and are anxious to make the data fit your own personal agenda, whatever that is. This is a pattern in your posts, not an aberration.

http://www.jgoins.com/core_melungeon.htm

http://www.cyndislist.com/melungeons.htm

"The line separating good and evil passes not through states, nor between classes nor between parties either — but right through the human heart." — Aleksandr Solzhenitsyn

robin  posted on  2007-04-15   10:40:09 ET  Reply   Trace   Private Reply  

My link indicated that the DNA survey showed the SAME THING. Jesus. And that there is not much difference in Portuguese and Italians and Irish genetically.

The dominant trait of Melungians is that they are Europeans who intermarried with native peoples. That is all. Not Arabs, Not Turks, Not any exotic people - unless you find someone with some Italian traits exotic.

As I already pointed out it was some uncommon ailments shared by some of these descendants

And I showed you that's a myth - and those ailments that some identified as Melungians are not in any way ETHNIC BASED nor does this population ever had a history of these ailments passed on generationally.

"The desire to rule is the mother of heresies." -- St. John Chrysostom

Destro  posted on  2007-04-15   12:55:58 ET  Reply   Trace   Private Reply  

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