In the United States, many legislators and public health officials are busy trying to make vaccines de facto compulsory—either by removing parental/personal choice given by existing vaccine exemptions or by imposing undue quarantines and fines on those who do not comply with the Centers for Disease Control and Prevention’s (CDC’s) vaccine edicts. Officials in California are seeking to override medical opinion about fitness for vaccination, while those in New York are mandating the measles-mumps-rubella (MMR) vaccine for 6-12-month-old infants for whom its safety and effectiveness “have not been established.”