"It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted physicians or authoritative medical guidelines. I take no pleasure in this conclusion, which I reached slowly and reluctantly over my two decades as an editor of The New England Journal of Medicine." -Marcia Angell, MD ("Drug Companies and Doctors: A story of Corruption." NY Review of Books, Jan. 15, 2009.)